Wayne L.H. Ho

PhD Candidate in Biomedical Sciences

Cancer Biologist | Glioblastoma | Cancer Metabolism and Cancer related GTPases | Animal Models

I am currently a Year 4 MPhil-PhD student of Biomedical Sciences at the Chinese University of Hong Kong (CUHK), where I am pursuing my research under the Cancer Biology & Experimental Therapeutics (CBET) thematic research program. My primary area of interest lies in understanding the intricate mechanisms underlying the development and progression of Glioblastoma Multiforme (GBM), a highly aggressive form of brain cancer.

In my research, I am specifically focused on investigating the role of mitotic key players in GBM carcinogenesis and progression. To achieve this, I employ advanced techniques such as protein structure analysis and Genetically Engineered Mouse Models (GEMMs). By examining the proteins involved in the mitotic process and their interactions within GBM cells, I aim to unravel the underlying molecular pathways that contribute to tumor growth and spread. Additionally, I utilize GEMMs to simulate key genetic alterations observed in GBM patients, allowing me to study the effects of these alterations on disease development and response to therapeutic interventions.

Through my research, I aspire to contribute to the growing body of knowledge in cancer biology and pave the way for novel therapeutic strategies targeting GBM. By elucidating the complex molecular mechanisms driving GBM progression, I hope to aid in the development of more effective treatments for patients and ultimately improve their quality of life.